“"It’s a hopeful, optimistic chapter,“ said Louise Rollins-Smith, PhD, associate professor of Pathology, Microbiology and Immunology, and a co-author of a study recently published in the journal Science.A collaborative group of investigators at multiple institutions showed that the fungal pathogen Batrachochytrium dendrobatidis continues to be as lethal now as it was more than 10 years ago.
The antimicrobial defenses produced by frog skin, however, appear to be more effective than they were before the fungal epidemic began.Rollins-Smith and her colleagues began studying how frogs combat B. dendrobatidis in Panama in 2004. For several years, Douglas Woodhams, PhD, a postdoctoral fellow on her team, and laboratory manager Laura Reinert made multiple trips to Central America to collect samples of frog skin secretions.
At the time, the fungal disease was spreading eastward from Costa Rica through Panama.“There was a predictable wave of pathogen moving to new populations,” said Rollins-Smith, who also traveled to Panama in 2010. “It gave us the opportunity to collect samples from populations of animals that had already encountered the epidemic and from the same species in places where the epidemic had not yet occurred.“The researchers found that skin secretions from frogs in areas with endemic (established) disease were more effective against the fungus compared to skin secretions from frogs that had not been exposed to the disease.”
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